Chronic cerebrospinal venous insufficiency (CCSVI or CCVI) is a term developed by Italian researcher Paolo Zamboni in 2008 to describe compromised flow of blood in the veins draining the central nervous system. Zamboni hypothesized that it played a role in the cause or development of MULTIPLE SCLEROSIS (MS). However, CCSVI may play a role also in other disease such as ASL, Parkinson, Meniere Syndrome and intractable headache.
Zamboni also devised a procedure which was termed by the media as “liberation procedure” or “liberation therapy”, involving angioplasty (or stenting) of certain veins in an attempt to improve blood flow.